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monagnady003
question on the nervous system

I've been doing an assignment in biology on the nervous system and a really obscure question came up that I've not read anything about either in my lesson or my textbook, and I can't find any information online either. It is: "Suggest the effect you would expect each substance named in the table [these are botulinum toxin, nicotine, and curare] to have on the postsynaptic generation of a nerve impulse." I really need to get this done before Saturday so any help will be greatly appreciated. xx


4 Comments
Chidume
Chidume
Botulinum toxins (BoNT) induce a relative muscle weakness by cleaving components of the presynaptic soluble NSF attachment protein receptor (SNARE) complex (essential for vesicular fusion), resulting in a significant reduction of acetylcholine release in the synaptic cleft
pearl345
pearl345
For Leaving cert , just mention that Botox blocks transmission of nerve impulses across the synaptic cleft .As it is a muscle relaxant ,hence why its used to relax wrinkles by freezing the muscle. Nicotine is a silly one as it is both a relaxant and stimulant and way beyond the scope of the leaving cert. This is not on LC the syllabus , ACETYLCHOLINE is the one you need to know , also have a n idea about serotinin dopamine etc. Bio Teacher
monagnady003
Thank you
bridgetown1
None of this is on the syllabus
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